MADURAI - 625002

(Established in 1985)



Phone: 0452 -2520565
Fax: 0452 -2530660
Email : crmeicmricmr.org.in
Website :  http://www.crme.res.in
Scope of Activities:

Situated at Madurai in Tamil Nadu, the Centre for Research in Medical Entomology (CRME), conducts research on various medico-entomological disciplines especially ecology, physiology, molecular biology, taxonomy, serology and control of vector-borne diseases such as Japanese encephalitis, lymphatic filariasis, dengue/chikungunya and malaria. The institute has three field stations, one each in Trikoilur, Vridhachalam and Chennai.

Thrust Areas:

    The following are the thrust areas of CRME
  • Surveillance and development of early-warning systems for epidemic outbreaks of vector-borne diseases.
  • Stratification of vector-borne diseases.
  • Survey of haematophagous arthropods.
  • Development of control strategies for vector-borne diseases.
  • Technology transfer to the user agencies.
International Recognition:

CRME has been recognized as WHO Collaborative Research Centre for research in lymphatic filariasis and dengue. During 2008-2011, CRME has been the TDR-WHO Centre for Asian Biosafety Training Course pertaining to Genetically Modified Mosquitoes.
Human Resource Development :

  • Three months project work to M.Sc. students from various Universities / Institutions.
  • Training to Public Health Staff / staff of other institutes on mosquito taxonomy, ecology, serology and virology.
Recognition for Doctorate/Masters by a University:

CRME is recognized for Ph.D programme by Madurai Kamaraj University, Madurai.

Major Achievements:

Significant achievements of CRME are the following:
  • Described five new mosquito species and reported several hitherto undescribed larval, pupal and adult stages of mosquito species.
  • Developed a simple identification key with illustrations to identify the vectors of JE.
  • The development of resistance in a wild population of the filariasis vector Cx.quinquefasciatus to Bacillus sphaericus (the microbial insecticide) was detected and reported for the first time in India.
  • Incrimination of Ocherotatus niveus (Aedes niveus) as a vector of sub-periodic bancroftian filariasis in the Andaman & Nicobar Islands.
  • Detection of JE virus antigen/isolation in desiccated vector mosquitoes. This technology was transferred to the Directorate of Public Health, Tamil Nadu, on 25th July, 2010.
  • Studies to show that larval populations of vectors were significantly enhanced by the use of synthetic nitrogenous fertilizers. Application of neem-coated urea was found to decrease the larval population of JE vectors.
  • Demonstrated effectively that vector control, when used as an adjunct to Mass Drug Administration (MDA), curtails transmission and prevents the resurgence of LF transmission.
  • Detection, isolation and serotyping of dengue virus by using Toxo-IFA system from Aedes albopictus, for the first time in Kerala.
  • Established presence of chikungunya virus in human sera in Lakshadweep Islands.
  • Demonstrated the use of mosquito exuvium as an alternate source of DNA, for the molecular characterization of different vector mosquitoes.

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